2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-

Product Name: 2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
CAS No.: 1235318-89-4
Chemical Name: 2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
Synonyms: ADX88178;ADX-88178;ADX88178, >98%;ADX-88178;ADX 88178;ADX88178;4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-2-Pyrimidinamine;5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine;2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-;5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine;Inhibitor,ADX 88178,mGluR,ADX88178,Metabotropic glutamate receptors,inhibit,ADX-88178
CBNumber: CB62594800
Molecular Formula: C12H12N6S
Formula Weight: 272.33
MOL File: 1235318-89-4.mol

More

Less

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Property

storage temp.: Store at -20°C
solubility: DMSO:16.67(Max Conc. mg/mL);61.21(Max Conc. mM)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-6961
Product name: ADX88178
Purity: 99.60%
Packaging: 5mg
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-6961
Product name: ADX88178
Purity: 99.60%
Packaging: 10mg
Price: $180
Updated: 2021/12/16

DC Chemicals

Product number: DC10465
Product name: ADX-88178
Purity: >98%
Packaging: 1g
Price: $1600
Updated: 2021/12/16

More

Less

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Chemical Properties,Usage,Production

Description

ADX-88178 is a novel potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor in rodent models of anxiety, obsessive compulsive disorder (OCD), fear, depression, and psychosis. ADX88178 dose-dependently reduced the number of buried marbles in the marble burying test and increased open-arm exploration in the elevated plus maze (EPM) test, indicative of anxiolytic-like efficacy.

target

ADX88178 is a metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Suppliers

China 39 United States 4 Global 43

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52927
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

1235318-89-4, 2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-Related Search:

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine

4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-2-Pyrimidinamine

ADX88178

ADX-88178

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine

ADX88178, >98%

ADX-88178;ADX 88178;ADX88178

Inhibitor,ADX 88178,mGluR,ADX88178,Metabotropic glutamate receptors,inhibit,ADX-88178

1235318-89-4